Collaborative Practice Agreement · PharmD

South Carolina Collaborative Practice Agreement for Pharmacists

Required. The Collaborative Practice Agreement is the written instrument South Carolina law names for a Pharmacist working with a physician. Below: the board that governs it, what it must contain, and the terms it has to carry.

Practice authoritySupervision required
Written agreementAgreement required
What South Carolina calls itCollaborative Practice Agreement
Governing boardSouth Carolina Board of Pharmacy
Agreement familyCollaborative Practice
Research date2026-09-03 · clauses 2026-09-03

Represents SC's Collaborative Practice Agreement (CPA) tier for medication-management services (Ch. 43), not ordinary dispensing licensure, which is out of scope here. The CPA framework is codified but implementation is contingent on the Board of Pharmacy and Board of Medical Examiners finalizing regulations governing its use — confirm those regulations are in effect before relying on this.

What a South Carolina Collaborative Practice Agreement must contain

Governed by the South Carolina Board of Pharmacy. Each numbered item is a statutory requirement the agreement must satisfy.

  1. South Carolina enacted legislation, effective May 18, 2026, authorizing a written collaborative practice agreement between a South Carolina-licensed pharmacist and a South Carolina-licensed physician (both actively practicing and physically located in the State) to provide evidence-based medication management and related patient care services supporting treatment goals the Physician establishes. As of the date of this Agreement, however, collaborative practice agreements may not be implemented until the South Carolina Board of Pharmacy and the South Carolina Board of Medical Examiners adopt regulations governing their use, which had not yet occurred. Until those regulations take effect, the Pharmacist practices under general South Carolina Board of Pharmacy licensure only, and no collaborative practice agreement under this statute is operative.

    Source: 2026 S.C. Act No. 166 (S.449), codified at S.C. Code §§ 40-43-245 and 40-47-205

  2. The Collaborative Practice Agreement on file also carries 1 registration, 1 authority clauses, generated in the document itself.

Statutes and rules cited

  1. 2026 S.C. Act No. 166 (S.449), codified at S.C. Code §§ 40-43-245 and 40-47-205statute

    Authorizes collaborative practice agreements between a South Carolina pharmacist and physician, effective May 18, 2026, but provides that such agreements may not be implemented until the South Carolina Board of Pharmacy and Board of Medical Examiners adopt implementing regulations.

Terms it has to carry

Ratio, proximity, chart review, meeting and prescribing terms the agreement has to carry, from the state's supervision rules.

Proximity

Not codified — left to the agreement

Supervision ratio

Not codified — no cap on file

Chart review

Not codified — left to the agreement

Meeting cadence

Not codified — left to the agreement

Prescriptive authority

Covered by the practice agreement · no controlled-substance authority

§40-43-30's CPA definition covers 'evidence-based medication management services' delegated by the physician (e.g. monitoring, education, assessments for identified patients) — no provision authorizing independent controlled-substance prescribing under a CPA was found in this research pass; set to False rather than assumed.

Written agreement

Required

The written CPA itself is defined in statute (§40-43-30), but by that same statute's terms 'collaborative practice agreements may not be implemented until' Board regulations governing their use take effect — verify current implementation status with the Board of Pharmacy.

Practice ownership (corporate practice of medicine)

Non-licensee ownership permitted — No pharmacist-ownership requirement was confirmed for a general pharmacy permit in this research pass — large non-pharmacist-owned chain pharmacies operate openly in SC, consistent with the permissive pattern seen in other states in this dataset.

A pharmacist-in-charge safeguard, not an ownership restriction, is the typical control mechanism — not separately confirmed against SC's Ch. 43 text in this pass.

Legal sources for these rules (2)
How the relationship works day to day
Who has to be where, how often you meet, and what the physician costs: Pharmacist in South Carolina on collaborativeagreement.com.

About South Carolina's rules

A physician may not hold practice agreements/scope-of-practice guidelines with more than a COMBINED 6 full-time-equivalent PA+NP+CNM+CNS at once (§40-47-195(D)(1)(c)) — a single shared cap, not four separate ones. A widely-repeated '3 PA' cap was repealed in 2019 (Act 32). SC remains restricted-practice for APRNs; a 2,000-hour full-practice-authority bill (S.45/H.3580) is pending, not yet law.

Other clinicians in South Carolina: see the state overview.