Collaborative Practice Agreement · NP

Louisiana Collaborative Practice Agreement (CPA) for Nurse Practitioners

Required. The Collaborative Practice Agreement (CPA) is the written instrument Louisiana law names for a Nurse Practitioner working with a physician. Below: the board that governs it, what it must contain, and the terms it has to carry.

Practice authorityConditional independence
Written agreementAgreement required
What Louisiana calls itCollaborative Practice Agreement (CPA)
Governing boardLouisiana State Board of Nursing and the Louisiana Board of Pharmacy
Agreement familyCollaborative Practice
Research date2026-09-03 · clauses 2026-09-03

Louisiana is a 'reduced practice' state — NPs generally practice under an LSBN-approved Collaborative Practice Agreement for as long as they practice. A codified but unconfirmed hours-based CPA exemption exists (see conditions) — treat as conditional pending verification, not confirmed full independence.

Independent practice requires: LA Admin. Code tit. 46 §7911.A.5 references an exemption from the collaborative practice agreement requirement after a threshold of prior collaborative-practice experience — secondary sources give conflicting hour figures (1,000 vs. 2,080 hours) and this research pass could not confirm the correct figure or exactly what authority the exemption confers (full independent diagnosis/prescribing vs. a narrower administrative exemption) — verify against LSBN rule text before relying on this for a compliance decision..

What a Louisiana Collaborative Practice Agreement (CPA) must contain

Governed by the Louisiana State Board of Nursing and the Louisiana Board of Pharmacy. Each numbered item is a statutory requirement the agreement must satisfy.

  1. The Nurse Practitioner shall practice pursuant to a Collaborative Practice Agreement ("CPA") with the Physician, approved by the Louisiana State Board of Nursing, as required by La. R.S. 37:1021 et seq. and La. Admin. Code tit. 46, Pt. XLV, ch. 79. The Physician shall hold a current, unrestricted Louisiana medical license in good standing, actively provide direct patient care in Louisiana, and practice in a specialty comparable in scope to the Nurse Practitioner's own. The Physician shall hold hospital privileges at any facility before the Nurse Practitioner receives privileges at that same facility.

  2. The CPA shall set out a plan of accountability covering the Nurse Practitioner's prescriptive authority and the Physician's responsibilities, and mutually agreed clinical practice guidelines, including a drug formulary. The Physician shall be available, though not necessarily physically present, for consultation, emergencies, and referral; if the Physician and any alternate are unavailable, the Nurse Practitioner may not diagnose or prescribe during that period. If the Nurse Practitioner has controlled-substance prescriptive authority, the Physician shall maintain a current DEA registration.

  3. The Collaborative Practice Agreement (CPA) on file also carries 1 scope, 1 education, 1 registration clauses, generated in the document itself.

Statutes and rules cited

  1. Louisiana Board of Pharmacyboard guidance

    State board administering the Louisiana Pharmacy Practice Act (La. R.S. 37:1161 et seq.) and its Collaborative Drug Therapy Management rules (La. Admin. Code tit. 46, Pt. LIII, Ch. 5).

Terms it has to carry

Ratio, proximity, chart review, meeting and prescribing terms the agreement has to carry, from the state's supervision rules.

Proximity

Available remotely (no on-site requirement)

No codified mile/minute radius or on-site standard; the collaborating physician must be available by telephone or direct telecommunication for consultation and emergencies when not physically present (LAC 46:XLV.7911). A 2014 LSBME proposal would have required a 1:4 ratio and quarterly on-site visits when not sharing a practice site — secondary-sourced and not confirmed as ever finalized; do not encode it as current law.

Supervision ratio

Not codified — no cap on file

Chart review

Not codified — left to the agreement

Meeting cadence

Annually

Clinical practice guidelines within the CPA (drug types/categories/schedules and generic-substitution options) must be mutually agreed upon and reviewed annually (LAC 46:XLV.7911). No shorter recurring chart-review or meeting cadence is codified.

Prescriptive authority

Separate prescribing terms required · controlled substances permitted

If the NP holds controlled-substance prescriptive authority, the collaborating physician must also hold current, unrestricted Louisiana and DEA registrations.

Written agreement

Required

Practice ownership (corporate practice of medicine)

Licensee-only ownership required — Professional Corporation/LLC under La. R.S. 12:901 et seq. — Louisiana's Professional Corporation Law generally restricts ownership of a nursing-services entity to licensees of that same profession; not independently confirmed for APRN-specific entity structures in this research pass.

Ownership and clinical collaboration are legally distinct: the collaborating physician under a CPA does not need to own the entity the NP practices through.

Legal sources for these rules (4)
How the relationship works day to day
Who has to be where, how often you meet, and what the physician costs: Nurse Practitioner in Louisiana on collaborativeagreement.com.

About Louisiana's rules

Louisiana remains a 'reduced practice' state for NPs — no SAVE Act-style full-practice-authority reform has passed. LA Admin. Code tit. 46 §7911.A.5 references an hours-based exemption from the CPA requirement for NP/CNM/CNS, but secondary sources give conflicting hour figures (1,000 vs. 2,080) and this pass could not confirm the exact threshold or resulting scope — verify directly with LSBN before relying on it.

Other clinicians in Louisiana: see the state overview.