Collaborative Practice Agreement · NP

Indiana Written Collaborative Practice Agreement for Nurse Practitioners

Required. The Written Collaborative Practice Agreement is the written instrument Indiana law names for a Nurse Practitioner working with a physician. Below: the board that governs it, what it must contain, and the terms it has to carry.

Practice authoritySupervision required
Written agreementAgreement required
What Indiana calls itWritten Collaborative Practice Agreement
Governing boardIndiana State Board of Nursing and the Indiana Board of Pharmacy
Agreement familyCollaborative Practice
Research date2026-08-21 · clauses 2026-09-03

Indiana is a reduced-practice state with no independent-practice or transition-to-practice pathway for NPs at any experience level — IC 25-23-1-19.4(c)'s collaboration requirement is career-long. Three recent bills that would have removed it all failed: HB 1116 (dead 4/24/2025), HB 1129 (dead 2/27/2026), and SB 60 (2026), which never left committee before sine die. AANP's tracker (updated 05/2026) still lists Indiana as Reduced Practice.

What a Indiana Written Collaborative Practice Agreement must contain

Governed by the Indiana State Board of Nursing and the Indiana Board of Pharmacy. Each numbered item is a statutory requirement the agreement must satisfy.

  1. The Nurse Practitioner shall practice pursuant to a written Collaborative Practice Agreement with the Physician for prescriptive authority, as required by Ind. Code § 25-23-1-19.4. The agreement shall address the scope of the Nurse Practitioner's prescriptive authority for legend drugs and controlled substances within both Parties' scopes of practice.

  2. The Nurse Practitioner shall submit documentation of their prescribing practices to the Physician within seven (7) days of request, including a random sample of at least five percent (5%) of charts or medications prescribed. Indiana law does not fix a numerical limit on the number of Nurse Practitioners with whom a physician may enter into a Collaborative Practice Agreement.

  3. The Written Collaborative Practice Agreement on file also carries 1 scope, 1 education, 1 registration clauses, generated in the document itself.

Statutes and rules cited

  1. Ind. Code § 25-26-16-4.5statute

    Authorizes a pharmacist to provide drug therapy management services to a patient under a written collaborative practice protocol with a supervising practitioner.

Terms it has to carry

Ratio, proximity, chart review, meeting and prescribing terms the agreement has to carry, from the state's supervision rules.

Proximity

No proximity requirement

No proximity, radius, or reachability standard is codified for APRNs. IC 25-23-1-19.4(c) requires only that the practice agreement 'set[] forth the manner in which' the APRN and the licensed practitioner 'will cooperate, coordinate, and consult with each other' — the parties define availability themselves. Coded NONE for absence of a codified distance rule; this is emphatically NOT independent practice (see `agreementRequired` above).

Supervision ratio

Not codified — no cap on file

Chart review

5% of charts · As needed (documentation of prescribing practices submitted to the collaborating practitioner within 7 days)

848 IAC 5-1-1(a)(7) requires the written practice agreement to describe 'the time and manner' of the licensed practitioner's review of the APRN's prescribing practices, with documentation submitted within seven (7) days and including at least a five percent (5%) random sampling of the charts and medications prescribed. Frequency is coded AS_NEEDED because the rule fixes the SIZE of the sample and the submission deadline but leaves the review cycle to the agreement — this is not a monthly or quarterly mandate. Confirmed current: the rule's history line shows 'Readopted filed 7/31/2024.' This is a prescriptive-authority requirement; a non-prescribing APRN is not subject to it.

Meeting cadence

Every 6 months, in person or via telehealth

No scheduled physician-APRN meeting is codified at all. BIANNUAL is coded for the only fixed recurring cycle located: prescriptive authority expires October 31 of the odd-numbered year following its grant or renewal and renews on a two-year cycle (IC 25-23-1-19.5(c)), and 848 IAC 5-1-3 requires a current signed and dated written collaborative practice agreement at each renewal. Read this as a two-yearly agreement-refresh obligation, not a meeting cadence.

Prescriptive authority

Covered by the practice agreement · controlled substances permitted

No Indiana-specific schedule restriction (e.g. a Texas-style Schedule II hospital/hospice limit) was located for APRNs in this pass. One narrow prohibition is visible only indirectly: every recent full-practice-authority bill (HB 1116, HB 1129, SB 60) proposed to ALLOW an APRN to prescribe a Schedule II controlled substance 'for weight reduction or to control obesity,' which implies that prohibition currently exists — but the underlying section was not located and read in this pass, so it is flagged rather than coded. Verify before relying on it.

Written agreement

Required

Unconditional. IC 25-23-1-19.4(c) requires an APRN to 'operate in collaboration with a licensed practitioner as evidenced by a practice agreement,' or alternatively under privileges granted by a hospital governing board — the agreement requirement attaches to APRN practice generally, not only to prescribing. Note the asymmetry in enforcement: the biennial random audit at IC 25-23-1-19.8(a) reaches only APRNs who hold prescriptive authority under IC 25-23-1-19.5, and only prescribers must file their agreement with the board (848 IAC 5-1-1(a)(7)). A non-prescribing APRN still needs an agreement under § 19.4(c) but has no filing or audit obligation attached to it.

Practice ownership (corporate practice of medicine)

Licensee-only ownership required — IC 25-22.5-1-2(a)(22) excludes from the Medical Practice Act a 'health care organization whose members, shareholders, or partners' are licensed as any of a named list that includes 'a registered or licensed practical nurse' and 'a certified nurse midwife.' Since IC 25-23-1-1(b) defines every Indiana APRN role as a registered nurse practicing in a specialty role, this file reads that list as reaching APRN-owned entities — a materially better ownership position than Texas's APRNs have, who are omitted from Tex. Bus. Orgs. Code § 301.012 entirely. FLAGGED AS AN INFERENCE: no Board of Nursing or Medical Licensing Board statement was found confirming the reading. A purely lay (unlicensed) owner is not on the § 2(a)(22) list at all, hence nonLicenseeOwnershipAllowed=False.

This analysis governs entity ownership only. It does not extend to any service outside the APRN's own scope — notably delegated medical-aesthetic procedures, which stay under the delegating physician's control via IC 25-22.5-1-2(a)(20) regardless of who owns the entity (see the `esthetician` entry).

Legal sources for these rules (9)
How the relationship works day to day
Who has to be where, how often you meet, and what the physician costs: Nurse Practitioner in Indiana on collaborativeagreement.com.

About Indiana's rules

Indiana requires a career-long collaborative practice agreement for every APRN role except CRNAs (IC 25-23-1-19.4(c)); APRN prescribers additionally face a codified 5%-of-charts random-sampling review (848 IAC 5-1-1). CRNAs instead face a stricter rule — physician direction and immediate presence (IC 25-23-1-30). Widely repeated reports that Indiana enacted full practice authority in 2026 are unsupported: HB 1116, HB 1129 and SB 60 all failed. Indiana's corporate-practice doctrine is comparatively permissive.

Other clinicians in Indiana: see the state overview.